abstract：:Burkholderia pseudomallei, the causative agent of melioidosis, is intrinsically resistant to many conventional antibiotics. Therefore, alternative antimicrobial agents such as antimicrobial peptides (AMPs) are extensively studied to combat this issue. Our study aims to identify and understand the mode of action of the...

journal_title：PeerJ

authors： Lee LF,Mariappan V,Vellasamy KM,Lee VS,Vadivelu J

更新日期：2016-10-25 00:00:00

abstract：:Climate change will significantly affect plant distribution as well as the quality of medicinal plants. Although numerous studies have analyzed the effect of climate change on future habitats of plants through species distribution models (SDMs), few of them have incorporated the change of effective content of medicina...

journal_title：PeerJ

authors： Guo Y,Wei H,Lu C,Gao B,Gu W

更新日期：2016-10-20 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the effects of low-volume high-intensity interval training and continuous low to moderate intensity training on quality of life, functional capacity and cardiovascular disease risk factors in cancer survivors. METHODS:Cancer survivors within 24 months post-diagnosis were r...

journal_title：PeerJ

authors： Toohey K,Pumpa KL,Arnolda L,Cooke J,Yip D,Craft PS,Semple S

更新日期：2016-10-20 00:00:00

abstract：BACKGROUND:VSEARCH is an open source and free of charge multithreaded 64-bit tool for processing and preparing metagenomics, genomics and population genomics nucleotide sequence data. It is designed as an alternative to the widely used USEARCH tool (Edgar, 2010) for which the source code is not publicly available, algo...

journal_title：PeerJ

authors： Rognes T,Flouri T,Nichols B,Quince C,Mahé F

更新日期：2016-10-18 00:00:00

abstract：:Parrotfish are fundamental species in controlling algal phase-shifts and ensuring the resilience of coral reefs. Nevertheless, little is known on their ecological role in the south-western Atlantic Ocean. The present study analysed the ontogenetic foraging activity and feeding selectivity of the Brazilian endemic parr...

journal_title：PeerJ

authors： Pereira PH,Santos M,Lippi DL,Silva P

更新日期：2016-10-12 00:00:00

abstract：:LIMKi 3 is a specific selective LIMK inhibitor against LIMK1 and LIMK2, while LIMK1 and LIMK2 are the main regulators of actin cytoskeleton to participate in many cell activities. However, the effect of LIMKi 3 in porcine oocyte meiosis is still unclear. The present study was designed to investigate the effects of LIM...

journal_title：PeerJ

authors： Jia RX,Duan X,Song SJ,Sun SC

更新日期：2016-10-12 00:00:00

abstract：BACKGROUND:Self-contained tests estimate and test the association between a phenotype and mean expression level in a gene set defined a priori. Many self-contained gene set analysis methods have been developed but the performance of these methods for phenotypes that are continuous rather than discrete and with multiple...

journal_title：PeerJ

authors： Walker JA

更新日期：2016-10-11 00:00:00

abstract：BACKGROUND:The rice receptor kinase XA21 confers robust resistance to the bacterial pathogen Xanthomonas oryzaepv. oryzae(Xoo). We previously reported that XA21 is cleaved in transgenic plants overexpressing XA21 with a GFP tag (Ubi-XA21-GFP) and that the released C-terminal domain is localized to the nucleus. XA21 car...

journal_title：PeerJ

authors： Wei T,Chen TC,Ho YT,Ronald PC

更新日期：2016-10-05 00:00:00

abstract：:Although the existence of coral-reef habitats at depths to 165 m in tropical regions has been known for decades, the richness, diversity, and ecological importance of mesophotic coral ecosystems (MCEs) has only recently become widely acknowledged. During an interdisciplinary effort spanning more than two decades, we c...

journal_title：PeerJ

authors： Pyle RL,Boland R,Bolick H,Bowen BW,Bradley CJ,Kane C,Kosaki RK,Langston R,Longenecker K,Montgomery A,Parrish FA,Popp BN,Rooney J,Smith CM,Wagner D,Spalding HL

更新日期：2016-10-04 00:00:00

abstract：:Many migratory bird species show high levels of site fidelity to their wintering sites, which confers advantages due to prior knowledge, but may also limit the ability of the individual to move away from degrading sites or to detect alternative foraging opportunities. Winter site fidelity often varies among age groups...

journal_title：PeerJ

authors： Lourenço PM,Alves JA,Reneerkens J,Loonstra AJ,Potts PM,Granadeiro JP,Catry T

更新日期：2016-09-28 00:00:00

abstract：BACKGROUND:Individuals with mental illness often experience stigmatization and encounter stereotypes such as being dangerous or unpredictable. To further improve measures against psychiatric stigma, it is of importance to understand its components. In this study, we attend to the step of separation between "us" and "th...

journal_title：PeerJ

authors： Makowski AC,Mnich EE,Angermeyer MC,von dem Knesebeck O

更新日期：2016-09-27 00:00:00

abstract：:Gelatin hydrogel crosslinked by microbial transglutaminase (mTG) exhibits excellent performance in cell adhesion, proliferation, and differentiation. We examined the gelation time and gel strength of gelatin/mTG hydrogels in various proportions to investigate their physical properties and tested their degradation perf...

journal_title：PeerJ

authors： Yang G,Xiao Z,Ren X,Long H,Qian H,Ma K,Guo Y

更新日期：2016-09-27 00:00:00

abstract：:We study the glycosylation processes that convert initially toxic substrates to nutritionally valuable metabolites in the flavonoid biosynthesis pathway of tomato (Solanum lycopersicum) seedlings. To estimate the reaction rates we use ordinary differential equations (ODEs) to model the enzyme kinetics. A popular choic...

journal_title：PeerJ

authors： Astola L,Stigter H,Gomez Roldan MV,van Eeuwijk F,Hall RD,Groenenboom M,Molenaar JJ

更新日期：2016-09-20 00:00:00

abstract：BACKGROUND:Highlighted text in the Internet (i.e., hypertext) is predominantly blue and underlined. The perceptibility of these hypertext characteristics was heavily questioned by applied research and empirical tests resulted in inconclusive results. The ability to recognize blue text in foveal and parafoveal vision wa...

journal_title：PeerJ

authors： Gagl B

更新日期：2016-09-20 00:00:00

abstract：:Spermatological characteristics of species from two monorchiid genera, Opisthomonorchis and Paramonorcheides, have been investigated, for the first time, by means of transmission electron microscopy. The ultrastructural study reveals that the mature spermatozoon of Opisthomonorchis dinema and Paramonorcheides selaris ...

journal_title：PeerJ

authors： Quilichini Y,Bakhoum AJ,Justine JL,Bray RA,Bâ CT,Marchand B

更新日期：2016-09-20 00:00:00

abstract：:Madagascar's subfossil record preserves a diverse community of animals including elephant birds, pygmy hippopotamus, giant lemurs, turtles, crocodiles, bats, rodents, and carnivorans. These fossil accumulations give us a window into the island's past from 80,000 years ago to a mere few hundred years ago, recording the...

journal_title：PeerJ

authors： Mathews JC,Samonds KE

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND:The composition of the salivary microbiota has been reported to differentiate between patients with periodontitis, dental caries and orally healthy individuals. To identify characteristics of diseased and healthy saliva we thus wanted to compare saliva metaproteomes from patients with periodontitis and denta...

journal_title：PeerJ

authors： Belstrøm D,Jersie-Christensen RR,Lyon D,Damgaard C,Jensen LJ,Holmstrup P,Olsen JV

更新日期：2016-09-14 00:00:00

abstract：:Coastal birds are critical ecosystem constituents on sandy shores, yet are threatened by depressed reproductive success resulting from direct and indirect anthropogenic and natural pressures. Few studies examine clutch fate across the wide range of environments experienced by birds; instead, most focus at the small si...

journal_title：PeerJ

authors： Maslo B,Schlacher TA,Weston MA,Huijbers CM,Anderson C,Gilby BL,Olds AD,Connolly RM,Schoeman DS

更新日期：2016-09-13 00:00:00

abstract：:Environmental heterogeneity affects not only the distribution of a species but also its local abundance. High heterogeneity due to habitat alteration and fragmentation can influence the realized niche of a species, lowering habitat suitability as well as reducing local abundance. We investigate whether a relationship ...

journal_title：PeerJ

authors： Basile M,Valerio F,Balestrieri R,Posillico M,Bucci R,Altea T,De Cinti B,Matteucci G

更新日期：2016-09-08 00:00:00

abstract：BACKGROUND:Cancer research is a national and international priority, with the efficiency and effectiveness of current anti-tumor therapies being one of the major challenges with which physicians are faced. OBJECTIVE:To assess the impact of exposure to tobacco smoke, arsenic, and phthalates on cervical cancer treatment...

journal_title：PeerJ

authors： Neamtiu IA,Bloom MS,Dumitrascu I,Roba CA,Pop C,Ordeanu C,Balacescu O,Gurzau ES

更新日期：2016-09-08 00:00:00

abstract：:The Pomacentridae (damselfish) and Apogonidae (cardinalfish) are among the most common fish families on coral reefs and in the aquarium trade. Members of both families undergo a pelagic larvae phase prior to settlement on the reef, where adults play key roles in benthic habitat structuring and trophic interactions. Fi...

journal_title：PeerJ

authors： Parris DJ,Brooker RM,Morgan MA,Dixson DL,Stewart FJ

更新日期：2016-08-31 00:00:00

abstract：BACKGROUND:The primary objective of this cross-sectional study was to estimate the crude, seasonal and cull-reason stratified prevalence of Salmonella fecal shedding in cull dairy cattle on seven California dairies. A secondary objective was to estimate and compare the relative sensitivity (Se) and specificity (Sp) for...

journal_title：PeerJ

authors： Abu Aboud OA,Adaska JM,Williams DR,Rossitto PV,Champagne JD,Lehenbauer TW,Atwill R,Li X,Aly SS

更新日期：2016-08-30 00:00:00

abstract：:Anemones of genus Exaiptasia are used as model organisms for the study of cnidarian-dinoflagellate (genus Symbiodinium) endosymbiosis. However, while most reef-building corals harbor Symbiodinium of clade C, Exaiptasia spp. anemones mainly harbor clade B Symbiodinium (ITS2 type B1) populations. In this study, we revea...

journal_title：PeerJ

authors： Chen WN,Hsiao YJ,Mayfield AB,Young R,Hsu LL,Peng SE

更新日期：2016-08-24 00:00:00

abstract：INTRODUCTION:The aim of this study was to determine the incidence rates of endometrial hyperplasia (EH) and endometrial cancer (EC) in the Republic of Korea using national insurance claim data generated from 2009 to 2012. MATERIALS AND METHODS:Data that were generated from 2009 to 2012 were sourced from the Korean Hea...

journal_title：PeerJ

authors： Yuk JS

更新日期：2016-08-24 00:00:00

abstract：:Footprint morphology (e.g., outline shape, depth of impression) is one of the key diagnostic features used in the interpretation of ancient vertebrate tracks. Over 80 tridactyl tracks, confined to the same bedding surface in the Lower Jurassic Elliot Formation at Mafube (eastern Free State, South Africa), show large s...

journal_title：PeerJ

authors： Sciscio L,Bordy EM,Reid M,Abrahams M

更新日期：2016-08-23 00:00:00

abstract：BACKGROUND:Information on cardiovascular gene transcription is fragmented and far behind the present requirements of the systems biology field. To create a comprehensive source of data for cardiovascular gene regulation and to facilitate a deeper understanding of genomic data, the CardioTF database was constructed. The...

journal_title：PeerJ

authors： Zhen Y

更新日期：2016-08-23 00:00:00

abstract：:Recently, numerous studies have observed changes in bird vocalizations-especially song-in urban habitats. These changes are often interpreted as adaptive, since they increase the active space of the signal in its environment. However, the proximate mechanisms driving cross-generational changes in song are still unknow...

journal_title：PeerJ

authors： Potvin DA,Curcio MT,Swaddle JP,MacDougall-Shackleton SA

更新日期：2016-08-16 00:00:00

abstract：:The study of material collected during routine monitoring surveys dealing with oil extraction and aquaculture in waters off Myanmar (North Andaman Sea) and in the Gulf of Thailand, respectively, allowed us to analyse the taxonomy and diversity of the polychaete genus Terebellides (Annelida). Three species were found, ...

journal_title：PeerJ

authors： Parapar J,Moreira J,Martin D

更新日期：2016-08-16 00:00:00

abstract：:As the most widely distributed snake in Eurasia, the adder (Vipera berus) has been extensively investigated in Europe but poorly understood in Asia. The Southern Altay Mountains represent the adder's southern distribution limit in Central Asia, whereas its population status has never been assessed. We conducted, for t...

journal_title：PeerJ

authors： Cui S,Luo X,Chen D,Sun J,Chu H,Li C,Jiang Z

更新日期：2016-08-16 00:00:00

abstract：:The blacklegged tick Ixodes scapularis is widely distributed in the United States and transmits multiple pathogens to humans, wildlife and domestic animals. Recently, several novel viruses in the family Bunyaviridae (South Bay virus (SBV) and Blacklegged tick phlebovirus (BTPV)) were identified infecting female I. sca...

journal_title：PeerJ

authors： Sakamoto JM,Ng TFF,Suzuki Y,Tsujimoto H,Deng X,Delwart E,Rasgon JL

更新日期：2016-08-11 00:00:00

abstract：:Background. Pollinators, which provide the agriculturally and ecologically essential service of pollination, are under threat at a global scale. Habitat loss and homogenisation, pesticides, parasites and pathogens, invasive species, and climate change have been identified as past and current threats to pollinators. Ac...

journal_title：PeerJ

authors： Brown MJ,Dicks LV,Paxton RJ,Baldock KC,Barron AB,Chauzat MP,Freitas BM,Goulson D,Jepsen S,Kremen C,Li J,Neumann P,Pattemore DE,Potts SG,Schweiger O,Seymour CL,Stout JC

更新日期：2016-08-09 00:00:00

abstract：:Background. A "cafeteria" diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy. Methods. Male Wistar rats were exposed for a month to "...

journal_title：PeerJ

authors： Sabater D,Agnelli S,Arriarán S,Romero Mdel M,Fernández-López JA,Alemany M,Remesar X

更新日期：2016-08-03 00:00:00

abstract：BACKGROUND:Digital medicine and smartphone-enabled health technologies provide a novel source of human health and human biology data. However, in part due to its intricacies, few methods have been established to analyze and interpret data in this domain. We previously conducted a six-month interventional trial examinin...

journal_title：PeerJ

authors： Gollamudi SS,Topol EJ,Wineinger NE

更新日期：2016-08-02 00:00:00

abstract：:To investigate community shelter effects of two invasive decapod species, Hemigrapsus sanguineus and Carcinus maenas, in the Long Island Sound (LIS), we deployed artificial shelters in the intertidal and immediate subtidal zones. These consisted of five groups during the summer: a control, a resident H. sanguineus mal...

journal_title：PeerJ

authors： Hudson DM,Reagan D,Crivello JF

更新日期：2016-07-27 00:00:00

abstract：:The evolution of the modern human (Homo sapiens) cranium is characterized by a reduction in the size of the feeding system, including reductions in the size of the facial skeleton, postcanine teeth, and the muscles involved in biting and chewing. The conventional view hypothesizes that gracilization of the human feedi...

journal_title：PeerJ

authors： Ledogar JA,Dechow PC,Wang Q,Gharpure PH,Gordon AD,Baab KL,Smith AL,Weber GW,Grosse IR,Ross CF,Richmond BG,Wright BW,Byron C,Wroe S,Strait DS

更新日期：2016-07-26 00:00:00

abstract：:Dendritic spines are described as neuronal protrusions. The morphology of dendritic spines and dendrites has a strong relationship to its function, as well as playing an important role in understanding brain function. Quantitative analysis of dendrites and dendritic spines is essential to an understanding of the forma...

journal_title：PeerJ

authors： Wang S,Chen M,Li Y,Shao Y,Zhang Y,Du S,Wu J

更新日期：2016-07-20 00:00:00

abstract：:The purpose of the study was to investigate the relationship between different exercise modes and visuospatial working memory in healthy older adults. A cross-sectional design was adopted. A total of 111 healthy older adults were enrolled in the study. They were classified by the exercise-related questionnaire to be i...

journal_title：PeerJ

authors： Guo W,Wang B,Lu Y,Zhu Q,Shi Z,Ren J

更新日期：2016-07-20 00:00:00

abstract：:The goal of this study was to assess the diagnostic accuracy of acute phase proteins and proinflammatory cytokines in sheep with pneumonic pasteurellosis. Blood samples were collected from 56 sheep (36 naturally infected with Pasteurella multocida and 20 healthy controls) belonging to one farm in Eastern region, Saudi...

journal_title：PeerJ

authors： El-Deeb WM,Elmoslemany AM

更新日期：2016-07-19 00:00:00

abstract：:Parallelism is important because it reveals how inherently stochastic adaptation is. Even as we come to better understand evolutionary forces, stochasticity limits how well we can predict evolutionary outcomes. Here we sought to quantify parallelism and some of its underlying causes by adapting a bacteriophage (ID11) ...

journal_title：PeerJ

authors： Miller CR,Nagel AC,Scott L,Settles M,Joyce P,Wichman HA

更新日期：2016-07-19 00:00:00

abstract：:Background. The ReproQuestionnaire (ReproQ) measures the client's experience with maternity care, following the WHO responsiveness model. In 2015, the ReproQ was appointed as national client experience questionnaire and will be added to the national list of indicators in maternity care. For using the ReproQ in quality...

journal_title：PeerJ

authors： Scheerhagen M,van Stel HF,Tholhuijsen DJ,Birnie E,Franx A,Bonsel GJ

更新日期：2016-07-13 00:00:00